Grants Calendar for Interdisciplinary ResearchLast Updated: October 19, 2026

This program invites applications from institutions that propose to establish core centers that are part of an integrated and existing program of nutrition and/or obesity research. The Nutrition Obesity Research Centers (NORC) program is designed to support and enhance the national research effort in nutrition and obesity. NORCs support three primary research-related activities: Research Core services, a Pilot and Feasibility program, and a Scientific Catalyst program, all designed to enhance the efficiency, productivity, effectiveness, and multidisciplinary nature of research in nutrition and obesity.

Humanity AI is a $500 million, five-year initiative co-chaired by Omidyar Network and the MacArthur Foundation, uniting ten foundations (including Ford, Mellon, Mozilla, Doris Duke, Lumina, Kapor, Siegel Family Endowment, and Packard) behind a pooled fund managed by Rockefeller Philanthropy Advisors. It backs civil-society organizations—not technical AI labs—working to ensure people and communities shape AI's future across five priority areas: strengthening labor and the economy, protecting the humanities and culture, improving security, safeguarding democracy, and advancing education. Its Communities Leading on AI open call supports U.S.-based community-led initiatives with grants of $75,000 to $1,000,000 for up to three years; initial applications are due October 21, 2026.

The National Geographic Society funds exploratory and conservation-driven research through recurring thematic calls related to its research priorities, focus areas, educational initiatives, and technology or solutions-oriented challenges. NGS issues multiple calls for proposals each year across its core focus areas, with new opportunities typically released every few months. Explorers grantees are eligible for future grants and funding from special initiatives. The Society has an extensive history of funding primate research and conservation efforts.

The Triangle Program, part of the Simons Foundation's Science, Society & Culture division, brings science and contemporary art together to engage audiences in creative ways. In Phase 1, Open Interval, an artist, a scientist and an arts organization apply together as a trio and undertake a multi-month period of sustained collaboration without a required immediate outcome. Phase 2 participants may then apply for Triangle project funding to produce new artworks investigating connections between art and scientific research.

This program supports academic institutions that provide high-quality interdisciplinary graduate and post-graduate training, research training, continuing education, and outreach in the core occupational safety and health disciplines of industrial hygiene, occupational health nursing, occupational medicine, and occupational safety, as well as allied disciplines.

RSF makes external grants for social science research projects that address questions of interest under its research priorities. RSF is accepting letters of inquiry (LOIs) under its core programs for Behavioral Science and Decision Making in Context (BSDMC) and Race, Ethnicity, and Immigration (REI) and its special initiatives on Immigration and Immigrant Integration (III) and Implications of the 2023 Supreme Court Decision to Ban Race-Conscious Admissions at Colleges and Universities for Educational Attainment and Economic Mobility (SCD23).

The purpose of this initiative is to: (1) support the efforts by R15-eligible Principal Investigators (PIs) to conduct rigorous basic and/or mechanistic pain research projects; (2) promote integrated, interdisciplinary research partnerships between R15-eligible PIs and additional investigators from U.S. domestic institutions, and (3) enhance the pain research environment at the R15-eligible institution for health professional trainees or undergraduate and/or graduate students by actively engaging them in the proposed pain research projects.

SISECSE is a two-week residential workshop that provides scholars of Eastern Europe time and space to dedicate to their own research and writing in a collaborative and interdisciplinary setting. ACLS in partnership with the Centre for Advanced Study Sofia convenes leading scholars from Eastern Europe and North America for a two-week residency in Blagoevgrad, Bulgaria. The program provides participating scholars with the opportunity to undertake local fieldwork, including archival or collections research, interviews, site surveys, or other forms of data collection. Made possible by Carl and Betty Pforzheimer.

The Robert H. N. Ho Family Foundation Early Career Research Fellowships in Buddhist Studies support recent PhDs and untenured faculty pursuing research projects in Buddhist studies. Fellows undertake scholarly research projects leading to publications, exhibitions, or other forms of dissemination. The program supports research across all aspects of Buddhist traditions, including textual studies, philosophy, art, history, anthropology of contemporary practice, and interdisciplinary approaches to Buddhism worldwide.

This fellowship supports dissertation projects that expand the traditional boundaries of doctoral research through new methodologies, innovative dissertation formats, and collaborations with partners within and beyond the academy. The program makes awards to doctoral students who show promise of leading their fields in important new directions. Fellowships are designed to intervene at the formative stage of dissertation development, before writing is advanced, supporting emerging scholars' innovative approaches to dissertation research. Made possible by a grant from the Mellon Foundation.

The Research-Practice Partnership (RPP) Grants Program supports education research projects that engage in collaborative and participatory partnerships with project budgets up to $400,000 and durations of up to three years. The Foundation views partnerships as an important approach to knowledge generation and the improvement of education, broadly construed. RPPs are intentionally organized to engage diverse forms of expertise and perspectives across practitioners, scholars, policymakers, and organizations in knowledge generation around pressing problems of practice and/or policy.

The aim of the Simons Collaborations in MPS program is to stimulate progress on fundamental scientific questions of major importance in mathematics, theoretical physics and theoretical computer science. The program funds collaborative teams rather than single investigators.

The ARCC Research Incentive Award supports architectural research that advances knowledge of the built environment. The program encourages interdisciplinary approaches to understanding architecture's role in addressing societal challenges including sustainability, resilience, health, and social equity.

The Robert Wood Johnson Foundation Health Policy Fellows program provides a comprehensive midcareer learning experience at the intersection of health, science, and policy. Fellows spend at least 12 months in Washington, D.C., beginning with an intensive orientation led by the National Academy of Medicine and followed by a full-time assignment in the federal government. The program develops health and behavioral health professionals' capacity to understand the federal policy process and use that leadership experience to advance policies, practices, and systems that improve health and its drivers nationwide.

The ACLS Digital Justice Seed Grants support early-stage planning and exploration of digital humanities projects centered on justice, equity, and historically marginalized communities. Seed grants enable scholars to conduct preliminary research, build collaborative teams, develop project frameworks, and prepare for full-scale implementation. The program is designed to lower barriers to entry for digital humanities work by funding the often-unfunded planning and discovery phases of innovative projects.

The National Aeronautics and Space Administration (NASA) Headquarters has released the solicitation “Space Technology Research Institutes (STRI26),” as an appendix to the Research and Technology Mission Directorate (RTMD) umbrella NASA Research Announcement (NRA) titled "Space Technology Research, Development, Demonstration, and Infusion 2026 (SpaceTech REDDI 2026).”.

This program will advance scientific community datasets to enable scientific discovery and innovation using artificial intelligence (AI) and other methods. Its goal is to increase the value that can be derived from existing scientific datasets by leveraging novel methods and artificial intelligence (AI). This will unlock new AI-driven insights. It can enable interdisciplinary research. It also enables investigations outside of the original motivation for data collection and analysis.

The Parkinson’s Research Program (PRP) Investigator-Initiated Research Award (IIRA) supports highly rigorous, multidisciplinary, high-impact research projects that have the potential to make an important contribution to Parkinson’s disease research. Research must address at least one of the four FY26 PRP Focus Areas. Distinctive Features: · Partnering Principal Investigator (PI) Option: Allows for more than one PI. One PI will be identified as the Initiating PI and will be responsible for the majority of the administrative tasks associated with application submission. The other PI(s) will be identified as Partnering PI(s), with a maximum of two Partnering PIs. · Preliminary data are required. · Clinical trials are allowed.

The Team Science Accelerator is a two-year pilot program supporting interdisciplinary teams that pursue high-risk, high-reward basic research across the physical sciences and adjacent fields. It is designed to help early- and midcareer faculty and independent scientists adopt effective team-science structures while tackling sharply defined scientific challenges in areas such as chemistry, physics, materials science, Earth and planetary science, astronomy, biochemistry, biophysics, and astrophysics. Selected teams also receive professional coaching, mentoring, facilitated workshops, and support to position their work for larger federal or external awards.

The goal of the Grants for Early Medical/Surgical Specialists' Transition to Aging Research (GEMSSTAR) program is to provide support for early-career clinician-scientists trained in medical or surgical specialties to launch careers as future leaders in aging- or geriatric-focused research. In support of the program's goal, this GEMSSTAR opportunity invites applications that propose to conduct transdisciplinary aging research that will yield pilot data and experience for subsequent aging research projects. The GEMSSTAR program encourages candidates to seek out a supportive research environment to further the program's objectives of fostering the development of early-career clinician-scientists in aging- or geriatric-focused research, particularly as it applies to their clinical specialty/discipline.

The Investigators in the Pathogenesis of Infectious Disease (PATH) program provides opportunities for assistant professors to bring multidisciplinary approaches to studying human infectious diseases. The program supports research that sheds light on the fundamentals that affect the outcomes of these encounters: how colonization, infection, commensalism, and other relationships play out at levels ranging from molecular interactions to systemic ones.

The Spinal Cord Injury Research Program mission is to fund research and encourage multidisciplinary collaborations for the development and translation of more effective strategies to improve the health and well-being of Service members, Veterans, and other individuals with spinal cord injury. The SCIRP has invested over $200 million into research and development efforts guided by the vision to advance the treatment and management of SCI and ameliorate its consequences relevant to injured Service members. The Clinical Translation Research Award supports translational research that will accelerate the movement of promising ideas in spinal cord injury research toward clinical applications. This award supports the translation of promising preclinical findings into clinical applications relevant to SCI, including studies that use patient-derived specimens, data, or observations to inform laboratory studies that will translate into clinical applications.

The Spinal Cord Injury Research Program mission is to fund research and encourage multidisciplinary collaborations for the development and translation of more effective strategies to improve the health and well-being of Service members, Veterans, and other individuals with spinal cord injury. The SCIRP has invested over $200 million into research and development efforts guided by the vision to advance the treatment and management of SCI and ameliorate its consequences relevant to injured Service members. The Clinical Trial Award supports the rapid implementation of clinical trials with the potential to have a significant impact on spinal cord injury. Clinical trials may be designed to evaluate promising new products, pharmacologic agents (drugs or biologics), devices, clinical guidance, and/or emerging approaches and technologies. Proposed projects may range from small proof-of-concept trials to larger trials to determine efficacy in relevant patient populations.

The Spinal Cord Injury Research Program mission is to fund research and encourage multidisciplinary collaborations for the development and translation of more effective strategies to improve the health and well-being of Service members, Veterans, and other individuals with spinal cord injury. The SCIRP has invested over $200 million into research and development efforts guided by the vision to advance the treatment and management of SCI and ameliorate its consequences relevant to injured Service members. The Investigator-Initiated Research Award supports hypothesis-driven research with the potential to make an important contribution to spinal cord injury research and/or patient care. The proposed research project should include a well-formulated, testable hypothesis based on a strong scientific rationale and study design, as well as include preliminary data relevant to SCI.

The Spinal Cord Injury Research Program mission is to fund research and encourage multidisciplinary collaborations for the development and translation of more effective strategies to improve the health and well-being of Service members, Veterans, and other individuals with spinal cord injury. The SCIRP has invested over $200 million into research and development efforts guided by the vision to advance the treatment and management of SCI and ameliorate its consequences relevant to injured Service members. The Translational Research Award supports translational research, defined as either the application of well-founded laboratory or other pre-clinical insight into a clinical trial or clinical study, or the use of patient-derived specimens, data, or observations to inform laboratory studies that will translate into clinical applications for spinal cord injury.

The aquatic contaminant risk project will develop a spatially explicit framework for assessing how contaminant and nutrient fluxes through adult aquatic insects affect aerial insectivorous birds. The synthesis will map risks from prey loss and dietary contaminant exposure across the United States and Europe, supporting habitat and species-management decisions at local, regional, and continental scales.

The Astronomy and Astrophysics Research Grants (AAG) Program is an inclusive and flexible funding opportunity to support research in the astronomical sciences. The Program provides individual investigator and collaborative research grants for observational, theoretical, laboratory, and archival data studies in astronomy and astrophysics. The Program also considers proposals for projects and tools that enable or enhance astronomical research. Proposals may span multiple disciplines and/or areas of study and may utilize multiple techniques.

The primary goal of the ECosystem for Leading Innovation in Plasma Science and Engineering (ECLIPSE) program is to identify and capitalize on opportunities for bringing fundamental plasma science investigations to bear on problems of societal and technological need within the scope of science and engineering supported by the participating NSF programs.

The Applied Mathematics program supports mathematics research motivated by and contributing to the solution of problems arising in science and engineering. Successful proposals must demonstrate mathematical innovation, as well as breadth and quality of impact on applications. Projects that additionally provide opportunities for rigorous mathematical training of junior applied mathematicians through their involvement in research are encouraged. The proposals considered by the Applied Mathematics program may range from single investigator to interdisciplinary team projects.

The Collaborative Program Grant supports integrated teams of three to six principal investigators addressing an ambitious, focused scientific goal that cannot be achieved through independent projects. Teams should demonstrate substantial synergy, meaningful interaction, and a unified strategy capable of producing major advances in the field.

The NSF FINDERS FOUNDRY program supports collaboration among K-12 educators, technologists, and researchers to develop innovative solutions to persistent challenges in learning and workforce development. These challenges are identified by K-12 students, families, and educators. The program aims to create and scale evidence-based practices, tools, and technologies that improve learning outcomes and prepare students for a digital, Artificial Intelligence (AI)-driven future. A key focus is early exposure to AI to build curiosity, understanding, and readiness for future careers. The program encourages partnerships across sectors - schools, universities, industry, government, and nonprofits - to co-design responsive, technology-based solutions.

The FY 2027 Multidisciplinary University Research Initiative (MURI) supports U.S. university teams conducting high-impact basic research on complex defense-relevant problems spanning multiple scientific disciplines. The joint competition includes research topics sponsored by the Air Force Office of Scientific Research (AFOSR), Army Research Office (ARO), and Office of Naval Research (ONR).

The NIH Research Program Project mechanism supports broadly based, multidisciplinary research organized around a major scientific objective or central theme relevant to participating NIH institutes and centers. Each program project combines interrelated research projects, an administrative core, and optional shared-resource cores to achieve objectives that require coordinated program-level effort.

The Newberry Library awards fellowships to scholars conducting research in its renowned humanities collections, particularly strong in American history, Native American and Indigenous studies, performing arts, postcards, and European civilization before 1700. Long-Term Fellowships are open to postdoctoral scholars for continuous residence at the Newberry for 4 to 9 months at $5,000 per month. Short-Term Fellowships are available to postdoctoral scholars, PhD candidates, and terminal-degree holders for 1 to 2 months at $3,000 per month. Fellows are supported by a collegial interdisciplinary community of researchers, curators, and librarians.

Terra Foundation Convening Grants support conversations, symposia, and workshops that stimulate interdisciplinary and intercultural exchange related to the visual arts of the United States and the Indigenous arts of North America.

This fellowship encourages scientists trained in quantitative fields such as mathematics, computer science, physics, and engineering to pursue research careers in computational biology applied to cancer. Fellows work under the joint mentorship of leaders in both computational science ("dry lab") and cancer biology ("wet lab"). The program addresses the growing need for computational biology leaders with expertise in both quantitative and biological sciences to advance cancer research through innovative data analysis and modeling approaches.

This program supports mathematical research in areas where computation plays a central and essential role, emphasizing analysis, development, and implementation of theoretically justified and efficient algorithms. The combination of these elements resulting in innovative computational methods is a hallmark of the program. Proposals ranging from single investigator to interdisciplinary team projects that not only create and analyze new computational mathematics techniques but also implement them to model, study, and solve important application problems are strongly encouraged, as is providing opportunities for rigorous mathematical training of junior computational mathematicians through research involvement.

The Expeditions program supports large, multidisciplinary teams pursuing ambitious, long-term foundational research to drive transformative advances in computing, information science and engineering.

This foundation supports ground-breaking research in: Character Virtue Development; Individual Freedom & Free Markets; Life Sciences; Mathematical & Physical Sciences; Public Engagement; and Religion, Science, and Society.

The W. M. Keck Research Program supports high-risk, high-impact basic science research that is distinctive and novel, questions the prevailing paradigm, or has the potential to open new territory in its field. It funds pioneering work in the basic physical, life, and biomedical sciences—including instrumentation development and engineering in service of fundamental scientific questions—at research universities, medical colleges, and independent research institutions.

This opportunity will support interdisciplinary teams addressing the Genesis Mission National Science and Technology Challenges to accelerate scientific discovery and research and development (R&D) workflows using novel artificial intelligence (AI) models and frameworks. By achieving AI advantage, these teams will advance the DOE's mission and ensure America's security and prosperity by addressing energy, environmental, and nuclear challenges through science and technology. Teams are encouraged to leverage the extensive scientific and data resources of the DOE/National Nuclear Security Administration (NNSA), the National Laboratories, U.S. industry, and academia.

ROSES-2025 is the omnibus NASA Research Announcement through which NASA encourages the participation of the space, Earth, and biological and physical science communities in the Science Mission Directorate's research and technology programs. Research and technology development activities are organized into five Science Divisions: 1. The Earth Science Research, Applied Sciences, Technology, and Data Systems Programs; 2. The Heliophysics Research Program; 3. The Planetary Science Research Program; 4. The Astrophysics Research Program; 5. The Biological and Physical Sciences Research Program.

The Burroughs Wellcome Fund launched the Career Awards at the Scientific Interface in 1999 to foster the early career development of researchers who are transitioning from training environments in the physical, mathematical, computational sciences and/or engineering into postdoctoral work in the biological sciences, and who are dedicated to pursuing a career in academic research.

American scientists and engineers will power the super intelligence (SI) revolution in science and innovation through the Genesis Mission . DOE SC hereby invites applications from United States (U.S.) Institutions of Higher Education and domestic doctoral-granting institutions to develop and demonstrate the effectiveness of novel four-year doctoral training pilots with dual competency in SI and another scientific discipline.

The Folger Institute Short-Term Fellowships support scholars whose work would benefit from significant primary research in the Folger's early modern collections for one, two, or three months. Stipends are $5,000 per onsite month and $4,000 per virtual month. Fellows may choose fully onsite, fully virtual, or hybrid configurations. The fellowships create a multidisciplinary community of inquiry around the history, literature, art, performance, philosophy, religion, and politics of the early modern world (1500-1750). Fellows engage with the world's largest Shakespeare collection, including 82 First Folios and over 60,000 manuscripts.

The purpose of this initiative is to support the development of innovative research centers to foster nursing-led programs that promote community-partnered research to address persistent health challenges. Center applications developed in response to this RFA should propose strategies to strengthen the research infrastructure by establishing or expanding centralized research resources in School or College of Nursing (SON/CON), developing and enhancing nurse-led interdisciplinary teams, and building expertise in community-partnered research through conducting pilot research that applies NINR's research lenses. Center strategies should be informed by NINRs mission and should meaningfully engage the community throughout all activities.

This program provides funding to develop shared-use research facilities or research resource facilities. These facilities are expected to meet the ongoing and future biomedical research needs, enable cutting-edge biomedical research or research on emerging health concerns, promote interdisciplinary collaborative research, cultivate the next generation of the biomedical research workforce, and sustain critical biomedical research resources for long-lasting impact.

This is a opportunity for a Limited Competition that invites applications from eligible organizations to apply. Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the applications will be peer-reviewed, and only meritorious applications will be considered for funding. This funding opportunity seeks to support the Cancer Advancement through Partnerships in Research and Infrastructure (CAPRI). The CAPRI Program establishes and strengthens comprehensive, mutually beneficial and meaningful partnerships between Resource Limited Institutions (RLIs) and NCI-designated Cancer Centers (CCs) to accelerate collaborative and innovative cancer.

This opportunity invites submission of investigator-initiated Program Project (P01) applications. The proposed Programs should address scientific areas relevant to the NIAID mission including: biology and pathogenesis of infectious microbes, including HIV; host-microbe interactions; mechanisms regulating immune system development and function across the lifespan, and in response to infectious pathogens; immune dysfunction resulting in allergy, asthma, autoimmunity, immunodeficiency, or transplant rejection; and translational research to develop vaccines, therapeutics, and diagnostics to prevent and treat infectious and immune-mediated diseases. Each application submitted to this NOFO must include at least two related, synergistic Research Projects that share a common central theme, focus, and/or overall objective; and an Administrative Core. An application may include Scientific Core(s), if needed for the proposed research.

The Specialized Programs of Research Excellence program supports multidisciplinary translational research centers focused on an organ-specific cancer or closely related group of cancers. Each SPORE must use human biology and reach a translational human endpoint within the project period, advancing prevention, early detection, diagnosis, or treatment through coordinated research projects and shared resources.

The Security, Privacy, and Trust in Cyberspace (SaTC 2.0) program aims to build trust in global cyber ecosystems. Proposals must be submitted pursuant to one of the following designations: Research (RES) designation for multidisciplinary studies; Education (EDU) designation for proposals focusing on education and workforce training in building trust in security, privacy, and resilience of cyberspace; and Seedling (SEED) category intended for special topics defined by accompanying Dear Colleague Letters.

This opportunity solicits applications from research partnerships formed by academic and industrial investigators to accelerate the development and adoption of promising bioengineering tools and technologies that can address important biomedical problems. The objectives are to establish these tools and technologies as robust, well-characterized solutions that fulfill an unmet need and are capable of enhancing our understanding of life science processes or the practice of medicine. Awards will focus on supporting multidisciplinary teams that apply an integrative, quantitative bioengineering approach to developing technologies. The goal of the program is to support technological innovations that deliver new capabilities which can realize meaningful solutions within 510 years.

This opportunity invites applications for Diabetes Research Centers (DRCs) that are designed to support and enhance the national research effort in diabetes, its complications, and related endocrine and metabolic diseases. The purpose of this Centers program is to bring together basic and clinical investigators to enhance communication, multidisciplinary collaboration, and effectiveness of ongoing research in Diabetes Research Center topic areas.

The Specialized Alcohol Research Centers program supports interdisciplinary, collaborative research on alcohol misuse, Alcohol Use Disorder, alcohol-related diseases, and associated biomedical, psychosocial, and population-health consequences across the lifespan. Centers are expected to create a critical mass of investigators in an innovative or understudied area, advance research methods, and mentor early-career researchers.

The Hydrosphere program supports research that advances understanding of the physics of Earth's water across the ocean, land, and atmosphere. It brings together ocean physics, terrestrial hydrology, and precipitation science to address fundamental questions about the distribution, movement, and transformation of water throughout the Earth system. Targeted research includes ocean salinity, snow depth, and precipitation measurements using commercial satellite data, while an additional cross-disciplinary component encourages broader connections with other Earth science fields. The program is designed to extend NASA investments in the Fate of River Export and Surface Hydrology field campaign, the NISAR mission, and the Commercial Satellite Data Acquisition program.

This opportunity supports hubs participating in a national consortium to accelerate the development of treatments for all by advancing clinical and translational science. Hubs will develop and disseminate scientific and operational innovations to improve the efficiency, quality, and impact of clinical research; promote partnerships that accelerate translational projects at local to national levels; address health disparities through cross‑institutional and community collaborations; support rapid responses to urgent public health needs; and provide comprehensive CTS training for clinical research professionals across disciplines.

CIRM's Discovery programs support research at different scales and levels of maturity, emphasizing multidisciplinary innovation, knowledge sharing, and leveraging synergies across CIRM-funded programs. DISC5 funds small, collaborative teams conducting high-risk, exploratory discovery research in stem cell biology, genetic research, and regenerative medicine. Each project must be co-led by a California-based Principal Investigator and Co-Investigator from different laboratories, with human stem cells or genetic research central to the approach. The objective is to accelerate the development of potential therapeutics and biomarkers across a diverse range of diseases and bottlenecks.

The Harry Frank Guggenheim Foundation supports research on violence, aggression, and dominance in relation to social change, intergroup conflict, war, crime, and family relationships. The Foundation funds scholarly research that advances understanding of the causes, manifestations, and control of violence and aggression, with priority given to research that addresses urgent, present-day problems of violence.

The goal of this program is to support collaborative translational research projects aligned with NIH efforts to enhance the translation of basic biological discoveries into clinical applications that improve health. It encourages high quality science demonstrating the potential to result in understanding an important disease process or lead to new therapeutic interventions, diagnostics, or prevention strategies within the research interests and priorities of the participating NIH Institutes/Centers (ICs).

The purpose of this funding opportunity is to encourage multidisciplinary investigators to develop new approaches or apply existing approaches in novel ways to measure brain activity, connectivity, genomics, or other aspects across the age spectrum of neurodevelopment. The overarching goal is to extend our understanding of brain development and aging, including studies of the neurodevelopmental origins of later health and disease. Research can include healthy human participants of any age, specific clinical groups such as those with cognitive, motor, or affective regulation challenges, and/or animal research on these domains of function.

This opportunity encourages collaborations between the life and physical sciences that: 1) apply a multidisciplinary bioengineering approach to the solution of a biomedical problem; and 2) integrate, optimize, validate, translate or otherwise accelerate the adoption of promising tools, methods, and techniques for a specific research or clinical problem in basic, translational, or clinical science and practice. An application may propose design-directed, developmental, discovery-driven, or hypothesis-driven research and is appropriate for small teams applying an integrative approach to increase our understanding of and solve problems in biological, clinical, or translational science. This NOFO will support clinical trials that test functionality or validate performance in the chosen setting. This NOFO is not intended to support conventional clinical trials that lack translation as the primary motivation. Applications that propose phase III clinical trials in any area of research are not sought by and will not be supported through this NOFO. This NOFO does not support commercial production.

This solicitation targets multidisciplinary teams who are embracing convergence research as a means of developing highly innovative solutions to complex research problems. GCR proposals are expected to be bold and address scientific or technical challenges and bottlenecks which if resolved have the potential to transform scientific understanding and solve vexing problems. Successful GCR projects are anticipated to lead to paradigm shifting approaches within disciplines, establishment of new scientific communities, or development of transformative technologies that have the potential for broad scientific or societal impact.

The NIH Cardiovascular Repository for Type 1 Diabetes (CaRe-T1D) was created to improve research on type 1 diabetes (T1D) and cardiovascular disease (CVD). Cardiovascular complications remain the top cause of death among people with T1D and greatly shorten lifespan. The mechanisms underlying atherosclerosis, cardiomyopathy, endothelial dysfunction, and cardiac autonomic neuropathy in T1D remain poorly understood. While managing traditional risk factors—such as high blood glucose, high blood pressure, and elevated cholesterol lower cardiovascular risk, a significant residual risk remains even with optimal control. In addition to atherosclerosis, both diastolic and systolic diabetic cardiomyopathy play a major role in morbidity and mortality among these patients. Currently, no therapies are specifically approved to prevent or treat these common and severe cardiovascular issues in T1D. The purpose of this NOFO is to promote collaborative and interdisciplinary research aimed at enhancing the understanding of the development of CVD in individuals with T1D and the differences with CVD in T1D by continuing the efforts of the CaRe-T1D consortium.

Invasive surgical procedures in humans offer the unique opportunity to intracranially record and stimulate neuronal activity within precisely localized brain structures, enabling high-impact human neuroscience investigations. This NOFO seeks exploratory research projects, from newly formed or established multi-disciplinary teams, to understand how dynamic activity of single cells and ensembles of neurons in spatially organized networks gives rise to the internal states we experience as sensations, perceptions, emotions, thoughts, and memories, and to observable motor and social behaviors.

The NLM institutional training program supports innovative predoctoral and postdoctoral programs that prepare researchers in biomedical informatics, data science, and artificial intelligence and machine learning. Programs may be new or renew existing NLM-supported training and should integrate advanced computational approaches with health and biomedical research across disciplines.

The Emerging Frontiers in Research and Innovation (EFRI) program serves a critical role in helping the NSF Directorate for Engineering focus on important emerging areas in a timely way. The EFRI program invests in potentially transformative ideas that offer the opportunity for significant shifts in foundational engineering knowledge. EFRI-funded research must have strong potential for long-term impact on strategic technology priorities and/or national science and technology (S&T) missions identified in the Administration's Fiscal Year (FY) 2028 Research and Development (R&D) Budget Priorities Memorandum. Such impacts need not be fully realized within the duration of the research period; however, proposers are expected to articulate how a proposal is use-inspired and may lay the foundations for stated priorities. This EFRI solicitation leverages a portfolio of both two-year EArly-concept Grants for Exploratory Research (EAGER) awards and larger four-year awards in response to Science: A New Golden Age, which calls for a more flexible set of funding mechanisms that match the scientific challenges they seek to address.

Formerly the Transatlantic Networks of Excellence Program, this initiative promotes internationally collaborative basic, translational and clinical research in cardiovascular and neurovascular disease. It brings together international teams with complementary expertise to work on a common thematic problem, aiming to generate knowledge that advances diagnosis, prevention and treatment. Early career investigators play a vital role in these networks, which provide strong context for training and career development. Open to investigators worldwide at academic research centers.

This opportunity supports projects at the intersection of substance use research and one or more of the following fields: Discovery and development of new chemical entities or biologics to advance therapeutic interventions for substance use disorders (SUDs) and drug dependence; Development and application of brain imaging tools or brain imaging methods; Application of innovative neurocognitive and behavioral science tools or paradigms; Application of advanced data science techniques and innovative computational methods, including artificial intelligence; Research that can lead to advancing basic, clinical, translational, epidemiological, or intervention science regarding substance use and HIV/AIDS.

Tiny Blue Dot Foundation seeks rigorous, empirical, statistically valid research on the neural, experiential, psychological, physiological, and social mechanisms involved in the Perception Box—the mental models that shape how people perceive and respond to the world. Projects should discover or develop tools and interventions that help people understand and gain agency over these mental models, measure the effectiveness of those approaches, and track related neural or psychological outcomes. Interdisciplinary methods spanning neuroscience, psychology, and social science are encouraged, as are multi-institutional collaborations and research with practical benefits for clinical or non-clinical populations.

The long-term goal of the Agriculture and Food Research Initiative - Strengthening Agricultural Systems (SAS) opportunity is to help transform the U.S. food and agricultural system to increase agricultural production while enhancing farmer prosperity. Achieving this goal will require transdisciplinary approaches to address current and future food and agricultural challenges within the context of the economic viability of farm operations, quality of life for farmers and society as a whole, and the most efficient use of resources.

This program supports innovative, cutting-edge research at the frontiers of the life sciences through international collaboration. Research Grants fund teams of scientists from different countries working on novel approaches to understanding complex mechanisms of living organisms. Program Grants support established teams while Early Career Grants target researchers within 10 years of PhD.

This program supports translational research projects focused on ovarian cancer, including studies on early detection, treatment resistance, and novel therapeutic approaches. The program encourages collaborative, multi-institutional research teams and projects that incorporate AI/ML applications, health equity considerations, and patient-centered outcomes.

The Creative Capital Award provides unrestricted project grants from $15,000 up to $50,000 to individual artists for the creation of innovative, original, and imaginative new artistic works. Funding supports new works in Visual Arts, Performing Arts (Dance, Theater, Music/Jazz), Film, and Literature, including multidisciplinary, technology, and socially engaged projects. Awardees also receive professional development support, industry connections, and community-building opportunities through the Creative Capital Artist Lab.

The Fire Science Innovations through Research and Education (FIRE) program invites innovative multidisciplinary and multisector investigations focused on convergent research and education activities in wildland fire. All areas of science, engineering, and education supported by the NSF are included in this program. Projects developed by a wide array of groups including, for example, academics, educators, scientists, community members, students, industry partners, practitioners, resource managers, and Tribal representatives, working together to generate new knowledge of the interactions among biological, social, geoscientific, and engineering processes encompassing multiple fields, scales, and perspectives on wildland fire are encouraged.

The FAIROS Program seeks to support a broad range of transformative open science activities including but not limited to: Research, education, and socio-technical cyberinfrastructure development capacities that advance sustainable multi-disciplinary findable, accessible, interoperable, reusable (FAIR) research data management (RDM) and open science capabilities; Piloting new models of scientific communication and publication that improve efficiency and accessibility; Developing FAIROS data portals, research data commons, RDM as a national service, and ;Lowering barriers to accessing, curating, integrating, linking, managing, sharing, and storing data across many disciplinary domains, irrespective of data size.

The Foundations for Digital Twins as Catalyzers of Biomedical Technological Innovation (FDT-BioTech) program supports inherently interdisciplinary research projects that underpin the mathematical and engineering foundations behind the development and use of digital twins and synthetic data in biomedical and healthcare applications, with a particular focus on digital, in silico models used in the evaluation of medical devices and the relevance of the developed models in addressing current and emerging challenges affecting the development and assessment of biomedical technologies. The goal of the FDT-BioTech initiative is to catalyze biomedical technological innovation through new foundational development of methods and algorithms relevant to digital twins and synthetic humans.

The Andy Warhol Foundation Arts Writers Grant supports emerging and established writers who write about contemporary visual art. Grants range from $15,000 to $50,000 in four categories: articles, books, short-form writing, and translation. The grants support projects addressing both general and specialized art audiences, from short reviews for magazines and newspapers to in-depth scholarly studies. The program also supports art writing that engages criticism through interdisciplinary methods and experiments with literary styles.

The Foundation funds research on neuroscience and society--how neuroscience informs and reflects society, and practical work to put those ideas into action. Projects may be informed by such fields as ethics, law, humanities, medicine, arts, social sciences, policy, education, journalism, and public engagement, and should address complex societal problems.

This opportunity encourages applications for Silvio O. Conte Centers for Basic Neuroscience or Translational Mental Health Research. The National Institute of Mental Health (NIMH) seeks teams of integrative researchers working at different levels of analysis and employing novel, and creative experimental approaches to address high-risk, high-impact questions with the primary objectives of: (a) advancing basic brain and behavior research that will uncover underlying mechanisms that could provide the foundation for understanding mental disorders; (b) supporting the integration and translation of basic and clinical neuroscience research on severe mental illnesses; (c) advancing our understanding of the neurobehavioral mechanisms and trajectories of psychopathology that begin in development. This program is intended only for projects that could not be achieved using other, more standard grant mechanisms.

The Centers for AIDS Research and Developmental Centers for AIDS Research program supports administrative coordination, shared research resources, expertise, and services that strengthen interdisciplinary HIV/AIDS research. Centers provide infrastructure that is not readily available through individual awards and foster collaboration across basic, clinical, behavioral, and population research.

The purpose of this notice of funding opportunity (NOFO) is to support multidisciplinary consortia of structural biologists, microbiologists, and associated experts to solve complex biological structures related to the prevention, treatment, and cure of HIV and other infectious diseases.

The overall goal of the MetNet is to advance our understanding of metastasis as a whole body, systems-level problem to develop a comprehensive and cohesive picture of the processes involved. Through this program, the NCI invites applications for MetNet Research Projects. These Research Projects should be defined as discrete entities that use systems-level approaches to address gaps and opportunities in metastasis research to integrate into the MetNet and complement ongoing research across the Network.

This program supports interdisciplinary research addressing complex social issues in Japan and internationally. The Foundation funds projects that integrate perspectives from multiple disciplines to generate knowledge and solutions for societal challenges. Priority areas include social cohesion, sustainability, and cross-cultural understanding.

The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. This opportunity invites researchers to submit applications for support of new exploratory and developmental research projects that address critical needs for Down syndrome projects, as articulated in the INCLUDE Project objectives. For example, such projects could assess the feasibility of a novel area of investigation or a new experimental system that has the potential to enhance health-related research.

The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. The purpose of this opportunity is to solicit Transformative Research Award applications to support individual scientists or groups of scientists proposing groundbreaking, exceptionally innovative, original, and/or unconventional research that has the potential to create new scientific paradigms, establish entirely new and improved clinical approaches, or develop transformative technologies related to Down syndrome. Applications are welcome in all topics relevant to Down syndrome-related research or its co-occurring conditions. No preliminary data are required. Projects must clearly demonstrate, based on the strength of the logic, a compelling potential to produce a major impact in research related to Down syndrome.

DISC4 supports large, multi-institutional teams conducting integrated discovery research to generate foundational insights into human disease and identify or validate therapeutic strategies, targets, or biomarkers. Core teams must include at least five California-based investigators and use human stem cells or genetic research as a central element of the work.

This opportunity supports transdisciplinary research teams seeking to develop mechanistic, biologically grounded explanations of how neural circuits and their cellular building blocks give rise to central nervous system (CNS) function. Teams must integrate expertise spanning molecular and cellular through systems neuroscience, with strong collaboration between experimental and computational investigators, to bridge cells, circuits, and behavior in a unified framework that yields mechanistic insight.Applications must explicitly connect three core elements: (1) characterization of circuit components (e.g., cell types and/or connectivity); (2) measurement of dynamic circuit activity, incorporating in vivo CNS recordings at cellular and sub-second temporal resolution;

The Just Tech Fellowship supports rigorous, original, and community-grounded work addressing how technology shapes society and public life. It is open to researchers, artists, journalists, technologists, and practitioners, with no formal degree requirement. The program provides a one-year unrestricted award of up to $60,000, plus monthly virtual gatherings, individualized mentoring, and one in-person workshop. Fellows must reside in the United States for the fellowship year; full-time students are not eligible.

This program supports career development for promising early-career researchers. The program funds five-year research and mentoring plans that significantly expand researchers' expertise in new disciplines, methods, and content areas.

The Small Research Grants on Education Program supports education research projects that will contribute to the improvement of education, broadly conceived, with budgets up to $50,000 for projects ranging from one to five years. Applications are accepted two times per year. This program is field-initiated and supports proposals from multiple disciplinary and methodological perspectives, both domestically and internationally.

The NIH Director's New Innovator Award supports early-stage investigators of exceptional creativity who propose bold and highly innovative research projects with the potential to produce a major impact on broad, important areas relevant to the mission of NIH. Applications in any area within the biomedical sciences are welcome; topics may involve basic, translational, or clinical research. The NIH Director's New Innovator Award complements other ongoing efforts by NIH and its Institutes and Centers to fund early-stage investigators. The NIH Director"s New Innovator Award is a component of the High-Risk, High-Reward Research (HRHR) program of the NIH Common Fund.

The National Institute on Deafness and Other Communication Disorders (NIDCD), with the National Institute of Biomedical Imaging and Bioengineering (NIBIB), aims to support the development and/or adaptation of transformative in vivo high-resolution imaging of the human olfactory system. Currently, there are limited non-invasive/minimally invasive technologies for imaging the living human peripheral and central olfactory system with high spatial and temporal resolution, which is essential to understanding underlying biological mechanisms and the etiology of olfactory disorders. Applications must leverage advanced non-invasive/minimally invasive imaging technologies to visualize peripheral (e.g., olfactory epithelium) and central olfactory (e.g., olfactory bulb) targets at a level previously unattainable. Projects should engage multidisciplinary teams combining expertise in olfaction, biomedical imaging, biochemistry, bioengineering, and biophysics.

The Pew Scholars Program in the Biomedical Sciences provides funding to young investigators of outstanding promise in science relevant to the advancement of human health. The program makes grants to selected academic institutions to support the independent research of outstanding individuals who are in their first few years of their appointment at the assistant professor level. Candidates must hold a doctorate in biomedical sciences, medicine, or a related field, including engineering or the physical sciences, run an independent lab, and hold a full-time assistant professor appointment. Candidates whose work is based on biomedical principles but who bring in concepts and theories from more diverse fields are encouraged to apply. The program does not fund clinical trials research.

The John W. Kluge Center at the Library of Congress awards up to 12 Kluge Fellowships annually to scholars in the humanities, social sciences, and professional fields such as architecture or law. Fellowships support residential research at the Library of Congress for periods of 4 to 11 months, drawing on the Library's vast collections including the world's largest law library, multilingual books and periodicals, manuscripts, maps, music, films, recorded sound, prints, and photographs. The Center encourages humanistic and social science research, with particular interest in interdisciplinary and cross-cultural projects. Fellows work in the Center's space in the Jefferson Building and engage with the Library's specialized staff and Washington's intellectual community.

The Superfund Hazardous Substance Research and Training Program, referred to as Superfund Research Program (SRP) Centers, supports problem-based, solution-oriented research Centers that consist of multiple, integrated projects representing both the biomedical and environmental science and engineering disciplines, as well as cores tasked with administrative functions (including Center leadership, data management, and training); translational research and engagement; and research support functions. The scope of the SRP Centers is taken directly from the Superfund Amendments and Reauthorization Act of 1986, which limits competition for this program to accredited institutes of higher education.

An NIH Common Fund program supporting exceptionally creative scientists pursuing highly innovative research.

Mathematical Sciences Research Institutes are national resources that aim to advance research in the mathematical sciences through programs supporting discovery and dissemination of knowledge in mathematics and statistics and enhancing connections to related fields in which the mathematical sciences can play important roles. Institute activities help focus the attention of some of the best mathematical minds on problems of particular importance and timeliness. Institutes are also community resources that involve a broad segment of U.S.-based mathematical sciences researchers in their activities.

Mission Office Innovative Solution Openings (ISO) provide a way to seek funds for individual research projects that fall outside the scope of an ARPA-H program or initiative, but that still aligns with an ARPA-H research focus areas. The Health Science Futures Office ISO supports research that removes scientific and technological limitations that stymie progress towards the health care of the future. The Proactive Health Office ISO supports research that focuses on preventative programs that reduce the likelihood that people become patients. The Resilient Systems Office ISO supports research that builds robust and integrated health care systems. The Scalable Solutions Office ISO supports research that addresses challenges to geography, distribution, manufacturing, data and information, and economies to promote equitable solutions.

Exploratory grantmaking is intended to bring community needs and priorities into sharper focus and allow the Foundation to determine whether there is a clear strategy and potential impact in a specific area. AI in Science focus areas include reproducibility and transparency of machine learning-enabled science; ways that the philosophy of science and related fields might help to inform the optimal uses of machine learning to produce new knowledge; and the relative value of foundation models vs. good old fashioned machine learning for scientific discovery. Automation in Science focus areas include: Advances in robotics can enable the automation of many aspects of scientific lab and field work, especially when coupled with AI to dramatically accelerate iterative cycles of discovery. Though not substantially funding the implementation of these systems at scale, the Foundation is currently exploring their optimal uses by researchers as well as the institutional structures to support them.

In each of its science grantmaking programs, the Foundation seeks proposals for original projects led by outstanding individuals or teams, which exhibit a high degree of methodological rigor, which have a high expected return to society, and for which funding from the private sector, government, or other foundations is not yet widely available. Research awards are made under the following priority areas: Economics; Energy and Environment; History of Science and Technology; Matter-to-Life; Sloan Digital Sky Survey; Small-Scale Fundamental Physics.

Coefficient Giving (formerly Open Philanthropy, renamed November 2025) is the dominant private funder of AI safety and alignment research, having directed roughly $336 million since 2017 toward reducing risks from advanced AI. It funds technical alignment research, AI governance, and efforts to ensure advanced AI systems are safe and beneficial. The organization operates through open Requests for Proposals, listed grant opportunities, and relationship-based giving for repeat grantees, with an emphasis on measurable reduction of catastrophic AI risk.

The AFRI Foundational and Applied Science Program supports grants in six AFRI priority areas to advance knowledge in both fundamental and applied sciences important to agriculture. The six priority areas are: Plant Health and Production and Plant Products; Animal Health and Production and Animal Products; Food Safety, Nutrition, and Health; Bioenergy, Natural Resources, and Environment; Agriculture Systems and Technology; and Agriculture Economics and Rural Communities. Research-only, extension-only, and integrated research, education and/or extension projects are solicited in this Notice of Funding Opportunities (NOFO).

This program provides financial assistance to support the conduct of research or a recipient’s portion of collaborative research consistent with the ITL’s missions to support research in the following fields: Advanced Network Technologies, Applied and Computational Mathematics, Artificial Intelligence, Big Data, Biometrics, Cloud Computing, Cyber-Physical Systems, Cybersecurity, Forensic Science, Health Information Technology, Human Factors and Usability, Information Access, Information Processing and Understanding, Internet of Things (IoT), Metrology Infrastructure for Modeling and Simulation, Privacy Engineering, and Statistics for Metrology.

The Naval Postgraduate School (NPS) is interested in receiving proposals for research initiatives that offer potential for advancement and improvement in the NPS core mission of graduate education and research. Readers should note that this is an announcement to declare NPS’s solicitation in competitive funding of meritorious research initiatives across a spectrum of science and engineering, business, politics and public/foreign policy, operational and information sciences, and interdisciplinary disciplines that are in line with the NPS’s graduate education and research mission.

The Gordon and Betty Moore Foundation advances scientific discovery, environmental conservation, and the special character of the San Francisco Bay Area. The Foundation invests for the long-term in scientifically sound strategies that produce measurable results and lasting benefits, with focus areas in science, environment, patient care, and the Bay Area. The Foundation seeks to create positive outcomes for future generations through sustained, evidence-based philanthropy.

The Mark Foundation provides grant support to an expanding network of scientists conducting research across cancer types, from individual investigators to multidisciplinary collaborative teams.

The Research on Research Security (RoRS) program will advance the understanding of the full scope, potential, challenges, and nature of the research on research security field through scholarly evidence.

The Directorate for Biological Sciences (NSF BIO) Core Research in Biological Sciences (BIO Core) funding opportunity supports foundational and interdisciplinary research projects that expand knowledge of biology at any level of organization, from the molecular to the biome scale. NSF BIO accepts proposals that cover scientific topics associated with legacy programs historically supported by NSF BIO and proposals that explore new areas of biological sciences. BIO Core funds single- and multi-investigator awards. The portfolio of awards is anticipated to include a range of budgets and durations, including exploratory projects of smaller scope and long-horizon projects that benefit from longer-term commitment. BIO Core awards are subject to the availability of funds.

The NSF Geosciences Research solicitation supports foundational research projects that advance the frontiers of knowledge across all areas of the geosciences. This solicitation calls for proposals in three programs: Atmospheric and Geospace Sciences (AGS) Program; Earth Sciences (EAR) Program; and Ocean Sciences (OCE) Program. These programs support projects that expand the frontiers of knowledge in science and technology. The programs encourage projects that advance research on Earth's atmosphere and the near-Earth space environment; solid Earth sciences and Earth surface processes; and all fields of ocean science. Projects may focus on foundational research in a specific domain or cover multiple disciplines. NSF is particularly interested in intellectually ambitious and potentially transformative foundational research. Proposals need not promise a near-term product, deployment, or commercial outcome, nor need they address later-stage development to be competitive.

This program supports fundamental research on the design, optimization, sustainability and resilience of infrastructure systems during normal operation and extreme events, such as natural hazards, to serve community needs.

OpenAI's Researcher Access Program provides subsidized API access to support research on the responsible deployment of AI and the societal impact of AI systems. Researchers can apply for up to $1,000 in OpenAI API credits, valid for 12 months, applicable to publicly available models. Areas of interest include alignment, fairness and representation, societal and economic impacts, misuse potential, human-AI interaction, generalization and transfer learning, and multimodal measurement. Applications are reviewed quarterly.

Research to Prevent Blindness funds research to develop treatments, prevent blindness, and restore vision. The Foundation supports innovative research projects in ophthalmology and vision science. Funding priorities include basic and clinical research that advances understanding of eye diseases and leads to new therapies. The Foundation invests in programs that strengthen research capacity, support early-career scientists, and promote collaboration across disciplines.

The Transformative Research Grant program supports large-scale education research projects that have the potential to fundamentally reshape understanding of pressing issues in education. It is the Spencer Foundation's largest funding opportunity and represents the culmination of the Foundation's research grant pathway, building on the smaller Vision Grants program. Eligible projects pursue ambitious, field-shaping questions and are expected to generate significant new knowledge and have broad impact on educational theory, policy, or practice. The program is open by invitation only to prior Vision Grant awardees, who may apply for up to three years following completion of their Vision Grant.

CHEERS was developed to discover and fund promising research in healthcare, sustainability, advanced technologies, and other fields as they work to solve some of the world’s most urgent problems.